STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tcp11l2T-complex 11, testis-specific-like 2. (529 aa)    
Predicted Functional Partners:
hmgb3a
High mobility group box 3a.
      
 0.833
clk4a
CDC-like kinase 4a; Belongs to the protein kinase superfamily.
      
 0.801
cirbpa
Cold-inducible RNA-binding protein a.
      
 0.663
nudcd2
NudC domain-containing 2.
      
 0.630
ppp1r16b
Protein phosphatase 1, regulatory subunit 16B.
      
 0.582
ENSDARP00000132336
Uncharacterized protein.
      
 0.581
ENSDARP00000140806
Si:ch211-199b20.3.
      
 0.581
rbm5
RNA-binding motif protein 5.
   
  
 0.572
p4ha1a
Prolyl 4-hydroxylase, alpha polypeptide I a.
      
 0.568
MED9
Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.555
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.