STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hcrtr2Hypocretin (orexin) receptor 2. (424 aa)    
Predicted Functional Partners:
hcrt
Hypocretin (orexin) neuropeptide precursor.
   
 0.982
aanat2
Arylalkylamine N-acetyltransferase 2.
   
  
 0.862
hdc
Histidine decarboxylase.
      
 0.807
nptx2b
Neuronal pentraxin IIb.
      
 0.801
dbh
Dopamine beta-hydroxylase (dopamine beta-monooxygenase).
      
 0.665
grk3
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
   
  0.618
prr16
Proline-rich 16.
      
 0.611
nptx2a
Neuronal pentraxin 2a.
      
 0.582
fev
Protein FEV; Functions as a transcriptional regulator. Functions in the differentiation and the maintenance of the central serotonergic neurons. May play a role in cell growth (By similarity); Belongs to the ETS family.
   
  
 0.576
zpd
Zona pellucida glycoprotein d.
      
 0.569
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.