Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
nr5a1bNovel protein similar to Carassius auratus nuclear hormone receptor FTZ-F1. (502 aa)    
Predicted Functional Partners:
nr0b1
Nuclear receptor subfamily 0, group B, member 1.
    
0.988
nr0b2a
Nuclear receptor subfamily 0, group B, member 2a.
   
0.882
hoxb7a
Homeobox protein Hox-B7a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
    
 
 0.844
nr0b2b
Nuclear receptor subfamily 0, group B, member 2b.
   
 0.807
amh
Anti-Mullerian hormone.
    
 
 0.781
ppargc1a
Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.
    
 
 0.776
star
Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity).
   
 
 0.772
cyp19a1a
Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
   
 
 0.700
dazap2
DAZ-associated protein 2.
      
 0.663
nr1h3
Nuclear receptor subfamily 1, group H, member 3.
   
0.640
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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