leng1 protein (Danio rerio) - STRING interaction network

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[Homology]

Score

leng1

Leukocyte receptor cluster (LRC) member 1. (276 aa)

Predicted Functional Partners:

fra10ac1

0.908

ppil1

0.897

ppig

0.881

syf2

0.865

cwc22

0.861

cdc40

0.860

ccdc12

0.853

ddx5

0.847

cactin

0.838

sde2

0.833

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cactin	ccdc12	ENSDARP00000078145	ENSDARP00000028398	Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family.	Coiled-coil domain-containing 12.	0.925
cactin	cdc40	ENSDARP00000078145	ENSDARP00000060431	Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family.	Cell division cycle 40 homolog (S. cerevisiae).	0.931
cactin	cwc22	ENSDARP00000078145	ENSDARP00000013971	Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family.	Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly.	0.975
cactin	ddx5	ENSDARP00000078145	ENSDARP00000055491	Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family.	DEAD (Asp-Glu-Ala-Asp) box helicase 5; Belongs to the DEAD box helicase family.	0.809
cactin	leng1	ENSDARP00000078145	ENSDARP00000029247	Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family.	Leukocyte receptor cluster (LRC) member 1.	0.838
cactin	ppig	ENSDARP00000078145	ENSDARP00000065255	Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family.	Peptidylprolyl isomerase G (cyclophilin G).	0.823
cactin	ppil1	ENSDARP00000078145	ENSDARP00000127620	Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.923
cactin	sde2	ENSDARP00000078145	ENSDARP00000043773	Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family.	Replication stress response regulator SDE2; Involved in both DNA replication and cell cycle control. Unprocessed SDE2 interacts with PCNA via its PIP-box. The interaction with PCNA prevents monoubiquitination of the latter thereby inhibiting translesion DNA synthesis. The binding of SDE2 to PCNA also leads to processing of SDE2 by an unidentified deubiquitinating enzyme, cleaving off the N-terminal ubiquitin-like domain. The resulting mature SDE2 is degraded by the DCX(DTL) complex in a cell cycle- and DNA damage dependent manner. Binding of SDE2 to PCNA is necessary to counteract dama [...]	0.987
cactin	syf2	ENSDARP00000078145	ENSDARP00000090723	Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family.	Pre-mRNA-splicing factor syf2; Involved in pre-mRNA splicing as component of the spliceosome.	0.937
ccdc12	cactin	ENSDARP00000028398	ENSDARP00000078145	Coiled-coil domain-containing 12.	Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family.	0.925
ccdc12	cdc40	ENSDARP00000028398	ENSDARP00000060431	Coiled-coil domain-containing 12.	Cell division cycle 40 homolog (S. cerevisiae).	0.985
ccdc12	cwc22	ENSDARP00000028398	ENSDARP00000013971	Coiled-coil domain-containing 12.	Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly.	0.950
ccdc12	ddx5	ENSDARP00000028398	ENSDARP00000055491	Coiled-coil domain-containing 12.	DEAD (Asp-Glu-Ala-Asp) box helicase 5; Belongs to the DEAD box helicase family.	0.808
ccdc12	leng1	ENSDARP00000028398	ENSDARP00000029247	Coiled-coil domain-containing 12.	Leukocyte receptor cluster (LRC) member 1.	0.853
ccdc12	ppig	ENSDARP00000028398	ENSDARP00000065255	Coiled-coil domain-containing 12.	Peptidylprolyl isomerase G (cyclophilin G).	0.853
ccdc12	ppil1	ENSDARP00000028398	ENSDARP00000127620	Coiled-coil domain-containing 12.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.973
ccdc12	sde2	ENSDARP00000028398	ENSDARP00000043773	Coiled-coil domain-containing 12.	Replication stress response regulator SDE2; Involved in both DNA replication and cell cycle control. Unprocessed SDE2 interacts with PCNA via its PIP-box. The interaction with PCNA prevents monoubiquitination of the latter thereby inhibiting translesion DNA synthesis. The binding of SDE2 to PCNA also leads to processing of SDE2 by an unidentified deubiquitinating enzyme, cleaving off the N-terminal ubiquitin-like domain. The resulting mature SDE2 is degraded by the DCX(DTL) complex in a cell cycle- and DNA damage dependent manner. Binding of SDE2 to PCNA is necessary to counteract dama [...]	0.969
ccdc12	syf2	ENSDARP00000028398	ENSDARP00000090723	Coiled-coil domain-containing 12.	Pre-mRNA-splicing factor syf2; Involved in pre-mRNA splicing as component of the spliceosome.	0.994
cdc40	cactin	ENSDARP00000060431	ENSDARP00000078145	Cell division cycle 40 homolog (S. cerevisiae).	Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family.	0.931
cdc40	ccdc12	ENSDARP00000060431	ENSDARP00000028398	Cell division cycle 40 homolog (S. cerevisiae).	Coiled-coil domain-containing 12.	0.985

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