Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mcf2aMCF.2 cell line-derived-transforming sequence a. (1111 aa)    
Predicted Functional Partners:
hmgxb4a
HMG box domain-containing 4a.
      
 0.950
megf6a
Multiple EGF-like-domains 6a.
    
 
 0.882
rhoac
Rho-related GTP-binding protein RhoA-C; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
    
 0.798
rab36
RAB36, member RAS oncogene family.
    
 
 0.723
prdm12b
PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily.
      
 0.713
cdc42l2
Cell division cycle 42-like 2.
    
 0.698
cldne
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.595
E7FGQ0_DANRE
Si:ch73-206d17.1.
      
 0.573
rac1a
Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1).
    
 0.538
rhogb
Ras homolog gene family, member Gb.
    
 0.520
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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