Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
gfapGlial fibrillary acidic protein; Belongs to the intermediate filament family. (444 aa)    
Predicted Functional Partners:
elavl3
ELAV-like protein; Belongs to the RRM elav family.
   
  
 0.914
olig2
Oligodendrocyte lineage transcription factor 2.
   
 
 0.911
LOC101885864
Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.864
fabp7a
Fatty acid-binding protein 7, brain, a; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
   
  
 0.847
sox2
Transcription factor Sox-2; Transcriptional activator. May function as a switch in neuronal development (By similarity). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity).
   
 
 0.838
s100b
S100 calcium-binding protein, beta (neural); Belongs to the S-100 family.
   
 
 0.834
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 
 0.832
glulc
Glutamine synthetase.
      
 0.826
glula
Glutamine synthetase.
      
 0.821
glulb
Glutamine synthetase.
      
 0.821
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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