Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
jkampJnk1/mapk8-associated membrane protein. (309 aa)    
Predicted Functional Partners:
lamtor2
Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity).
      
 0.739
mapkap1
MAPK-associated protein 1.
      
 0.685
mapk6
Extracellular signal-regulated kinase 3.
      
 0.594
map3k2
Mitogen-activated protein kinase kinase kinase 2.
      
 0.570
mapkapk2a
Mitogen-activated protein kinase-activated protein kinase 2a; Belongs to the protein kinase superfamily.
      
 0.558
map3k1
Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase.
      
 0.553
mapk10
Mitogen-activated protein kinase.
    
 
 0.518
rbm25a
RNA-binding motif protein 25a.
 
      0.506
mapk9
Mitogen-activated protein kinase.
    
 
 0.474
dusp10
Dual-specificity phosphatase 10.
   
  
 0.472
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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