Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ccdc25Coiled-coil domain-containing protein 25; Belongs to the CCDC25 family. (207 aa)    
Predicted Functional Partners:
tmem115
Transmembrane protein 115.
      
 0.902
LOC100151570
Uncharacterized protein.
      
 0.876
morn5
MORN repeat-containing protein 5.
      
 0.861
cdadc1
Cytidine and dCMP deaminase domain-containing protein 1.
      
 0.816
ubl7b
Ubiquitin-like 7b (bone marrow stromal cell-derived).
      
 0.812
tmem135
Transmembrane protein 135.
      
 0.790
ndufaf6
NADH:ubiquinone oxidoreductase complex assembly factor 6.
      
 0.773
tmem184a
Transmembrane protein 184a.
      
 0.746
iws1
TFIIS N-terminal domain-containing protein.
      
 0.714
nhlrc2
NHL repeat-containing 2.
      
 0.679
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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