Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E7F7I7_DANRESi:ch211-196h16.12. (155 aa)    
Predicted Functional Partners:
si:dkey-27j5.5
Si:dkey-27j5.5.
   
 0.779
zgc:56628
Zgc:56628.
      
 0.739
kcnip3b
Kv channel-interacting protein 3b, calsenilin.
      
 0.594
gfra3
GDNF family receptor alpha 3.
   
  
 0.588
meis2a
Meis homeobox 2a.
    
 
 0.582
tmsb1
Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family.
      
 0.561
cldni
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.560
rasd1
RAS, dexamethasone-induced 1.
    
 0.523
gadd45bb
Growth arrest and DNA-damage-inducible, beta like.
      
 0.489
pbx1a
Pre-B-cell leukemia transcription factor 1a.
      
 0.466
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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