Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ucmaaUpper zone of growth plate and cartilage matrix-associated a. (135 aa)    
Predicted Functional Partners:
ggcx
Gamma-glutamyl carboxylase.
      
 0.782
mgp
Matrix Gla protein.
   
  
 0.752
camk1da
Calcium/calmodulin-dependent protein kinase 1Da; Belongs to the protein kinase superfamily.
      
 0.662
efcab2
EF-hand calcium-binding domain 2.
      
 0.609
fgf10b
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.596
vkorc1
Vitamin K epoxide reductase complex, subunit 1.
      
 0.595
ncam3
Neural cell adhesion molecule 3.
      
 0.574
cdc123
Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle; Belongs to the CDC123 family.
      
 0.556
hace1
E3 ubiquitin-protein ligase HACE1; E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division.
      
 0.545
tmem244
Transmembrane protein 244.
      
 0.533
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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