Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ube3dUbiquitin protein ligase E3D. (388 aa)    
Predicted Functional Partners:
cpsf3
Cleavage and polyadenylation-specific factor 3.
    
 
 0.960
memo1
Protein MEMO1; May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling (By similarity); Belongs to the MEMO1 family.
    
   0.876
ube2c
Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.798
pudp
Pseudouridine 5'-phosphatase.
      
 0.771
cyb5r4
Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
      
 0.748
dop1a
DOP1 leucine zipper-like protein A.
      
 0.738
prss35
Protease, serine, 35.
      
 0.704
pnpla4
Patatin-like phospholipase domain-containing 4.
      
 0.680
cstf3
Cleavage stimulation factor, 3' pre-RNA, subunit 3.
      
 0.667
adnp2a
ADNP homeobox 2a.
      
 0.661
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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