| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cyp2k22 | dio1 | ENSDARP00000012186 | ENSDARP00000121555 | Cytochrome P450, family 2, subfamily K, polypeptide 22; Belongs to the cytochrome P450 family. | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). | 0.446 |
| cyp2k22 | slco1f4 | ENSDARP00000012186 | ENSDARP00000150107 | Cytochrome P450, family 2, subfamily K, polypeptide 22; Belongs to the cytochrome P450 family. | Solute carrier organic anion transporter family member. | 0.900 |
| cyp2k22 | sult1st2 | ENSDARP00000012186 | ENSDARP00000030476 | Cytochrome P450, family 2, subfamily K, polypeptide 22; Belongs to the cytochrome P450 family. | Cytosolic sulfotransferase 2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L-thyronine), T4 (thyroxine), estrone and DOPA. | 0.664 |
| cyp2k22 | sult2st3 | ENSDARP00000012186 | ENSDARP00000036121 | Cytochrome P450, family 2, subfamily K, polypeptide 22; Belongs to the cytochrome P450 family. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.974 |
| dio1 | cyp2k22 | ENSDARP00000121555 | ENSDARP00000012186 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). | Cytochrome P450, family 2, subfamily K, polypeptide 22; Belongs to the cytochrome P450 family. | 0.446 |
| dio1 | slco1f4 | ENSDARP00000121555 | ENSDARP00000150107 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). | Solute carrier organic anion transporter family member. | 0.652 |
| dio1 | sult1st2 | ENSDARP00000121555 | ENSDARP00000030476 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). | Cytosolic sulfotransferase 2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L-thyronine), T4 (thyroxine), estrone and DOPA. | 0.498 |
| dio1 | sult2st3 | ENSDARP00000121555 | ENSDARP00000036121 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.475 |
| slco1f4 | cyp2k22 | ENSDARP00000150107 | ENSDARP00000012186 | Solute carrier organic anion transporter family member. | Cytochrome P450, family 2, subfamily K, polypeptide 22; Belongs to the cytochrome P450 family. | 0.900 |
| slco1f4 | dio1 | ENSDARP00000150107 | ENSDARP00000121555 | Solute carrier organic anion transporter family member. | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). | 0.652 |
| slco1f4 | sult1st2 | ENSDARP00000150107 | ENSDARP00000030476 | Solute carrier organic anion transporter family member. | Cytosolic sulfotransferase 2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L-thyronine), T4 (thyroxine), estrone and DOPA. | 0.836 |
| slco1f4 | sult2st3 | ENSDARP00000150107 | ENSDARP00000036121 | Solute carrier organic anion transporter family member. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.935 |
| sult1st2 | cyp2k22 | ENSDARP00000030476 | ENSDARP00000012186 | Cytosolic sulfotransferase 2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L-thyronine), T4 (thyroxine), estrone and DOPA. | Cytochrome P450, family 2, subfamily K, polypeptide 22; Belongs to the cytochrome P450 family. | 0.664 |
| sult1st2 | dio1 | ENSDARP00000030476 | ENSDARP00000121555 | Cytosolic sulfotransferase 2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L-thyronine), T4 (thyroxine), estrone and DOPA. | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). | 0.498 |
| sult1st2 | slco1f4 | ENSDARP00000030476 | ENSDARP00000150107 | Cytosolic sulfotransferase 2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L-thyronine), T4 (thyroxine), estrone and DOPA. | Solute carrier organic anion transporter family member. | 0.836 |
| sult1st2 | sult1st3 | ENSDARP00000030476 | ENSDARP00000006665 | Cytosolic sulfotransferase 2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L-thyronine), T4 (thyroxine), estrone and DOPA. | Cytosolic sulfotransferase 3; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including dopamine, T3 (triiodo-L-thyronine), T4 (thyroxine), estrone, DHEA (dehydroepiandrosterone), flavonoids, isoflavonoids and other phenolic compounds. | 0.488 |
| sult1st2 | sult2st1 | ENSDARP00000030476 | ENSDARP00000048631 | Cytosolic sulfotransferase 2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L-thyronine), T4 (thyroxine), estrone and DOPA. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.644 |
| sult1st2 | sult2st2 | ENSDARP00000030476 | ENSDARP00000140128 | Cytosolic sulfotransferase 2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L-thyronine), T4 (thyroxine), estrone and DOPA. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.600 |
| sult1st2 | sult2st3 | ENSDARP00000030476 | ENSDARP00000036121 | Cytosolic sulfotransferase 2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L-thyronine), T4 (thyroxine), estrone and DOPA. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.636 |
| sult1st2 | sult4a1 | ENSDARP00000030476 | ENSDARP00000132405 | Cytosolic sulfotransferase 2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L-thyronine), T4 (thyroxine), estrone and DOPA. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.596 |