STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmc1aProteasome (Prosome, macropain) 26S subunit, ATPase, 1a; Belongs to the AAA ATPase family. (440 aa)    
Predicted Functional Partners:
psmd14
Proteasome 26S subunit, non-ATPase 14.
   
 0.996
psmc3
Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.
  
0.995
psmd1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
   
 0.995
psmc2
Proteasome (Prosome, macropain) 26S subunit, ATPase 2; Belongs to the AAA ATPase family.
  
0.994
psmd3
Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 3.
   
 0.994
psmd6
Proteasome 26S subunit, non-ATPase 6.
   
 0.994
psmd12
Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12.
   
 0.994
psmc4
Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.
  
0.993
psmc6
Proteasome (Prosome, macropain) 26S subunit, ATPase, 6; Belongs to the AAA ATPase family.
  
0.993
psmc5
Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family.
  
0.993
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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