Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
asb1Ankyrin repeat and SOCS box-containing 1. (335 aa)    
Predicted Functional Partners:
cul5a
Cullin 5a; Belongs to the cullin family.
    
 
 0.961
cul5b
Cullin 5b; Belongs to the cullin family.
    
 
 0.882
elob
Elongin B.
    
 
 0.844
X1WBN9_DANRE
Uncharacterized protein.
    
 
 0.844
eloca
Elongin C paralog a; Belongs to the SKP1 family.
    
 
 0.834
elocb
Elongin C paralog b; Belongs to the SKP1 family.
    
 
 0.834
asb6
Ankyrin repeat and SOCS box-containing 6.
  
 
 
 0.793
traf3ip1
TRAF3-interacting protein 1; Plays an inhibitory role on IL13 signaling by binding to IL13RA1 and recruits TRAF3 and DISC1 to the microtubules. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis (By similarity).
 
  
 
 0.758
asb10
Ankyrin repeat and SOCS box-containing 10.
  
   
 0.727
tbl2
Transducin beta-like 2.
    
 
 0.636
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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