Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
slc5a8lSodium-coupled monocarboxylate transporter 1; Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)- dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D- lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5- aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. M [...] (610 aa)    
Predicted Functional Partners:
slc22a13a
Solute carrier family 22 member 13a.
   
 
 0.745
slc25a55b
Solute carrier family 25 member 55b; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.738
zp3f.2
Zona pellucida glycoprotein 3f, tandem duplicate 2.
      
 0.719
slc36a4
Solute carrier family 36 member 4.
   
  
 0.675
sycp1
Synaptonemal complex protein 1.
      
 0.668
aqp8b
Aquaporin-8bb; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
 
 0.602
sb:cb1081
Si:ch73-252p3.1.
      
 0.585
or115-15
Odorant receptor, family F, subfamily 115, member 15.
      
 0.571
slc5a9
Sodium/glucose cotransporter 4; Probable sodium-dependent sugar transporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
0.561
tspan2a
Tetraspanin.
      
 0.560
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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