Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rilpl2RILP-like protein 2; Involved in cell shape and neuronal morphogenesis, positively regulating the establishment and maintenance of dendritic spines. Plays a role in cellular protein transport (By similarity); Belongs to the RILPL family. (195 aa)    
Predicted Functional Partners:
rab10
RAB10, member RAS oncogene family.
    
 
 0.909
rab8a
RAB8A, member RAS oncogene family.
   
 
 0.888
rab8b
RAB8B, member RAS oncogene family.
   
 
 0.825
ppm1h
Protein phosphatase 1H.
      
 0.807
rab13
Ras-related protein Rab-13; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in endocytic recycling and may regulate the transport to the plasma membrane of transmembrane proteins. May regulate the assembly and the activity of tight jun [...]
   
 
 0.757
rab36
RAB36, member RAS oncogene family.
      
 0.744
rab15
RAB15, member RAS oncogene family.
    
 
 0.726
megf8-2
Multiple EGF-like-domains 8.
    
 
 0.726
rab35b
RAB35, member RAS oncogene family b.
      
 0.715
garem
GRB2-associated and regulator of MAPK protein 1; Adapter protein that may provide a link between cell surface epidermal growth factor receptor and the MAPK/ERK signaling pathway. May promote cell proliferation (By similarity).
   
 
 0.664
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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