STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rilpl2RILP-like protein 2; Involved in cell shape and neuronal morphogenesis, positively regulating the establishment and maintenance of dendritic spines. Plays a role in cellular protein transport (By similarity); Belongs to the RILPL family. (195 aa)    
Predicted Functional Partners:
rab10
RAB10, member RAS oncogene family.
    
 
 0.926
rab8a
RAB8A, member RAS oncogene family.
   
 
 0.835
rab36
RAB36, member RAS oncogene family.
      
 0.809
ppm1h
Protein phosphatase 1H.
      
 0.772
myo5c
Myosin VC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.739
zp2.6
Zona pellucida glycoprotein 2, tandem duplicate 6.
      
 0.720
rab13
Ras-related protein Rab-13; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in endocytic recycling and may regulate the transport to the plasma membrane of transmembrane proteins. May regulate the assembly and the activity of tight jun [...]
   
 
 0.706
rnaset2
Ribonuclease T2; Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA.
   
  
 0.690
rab8b
RAB8B, member RAS oncogene family.
   
 
 0.677
garem
GRB2-associated and regulator of MAPK protein 1; Adapter protein that may provide a link between cell surface epidermal growth factor receptor and the MAPK/ERK signaling pathway. May promote cell proliferation (By similarity).
   
 
 0.676
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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