Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
glra4aGlycine receptor, alpha 4a; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)    
Predicted Functional Partners:
gphnb
Gephyrin2 isoform.
    
 
 0.863
gphna
Gephyrin a.
    
 
 0.861
gprc5bb
G protein-coupled receptor, class C, group 5, member Bb.
      
 0.739
glrbb
Glycine receptor beta subunit 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
0.738
glrba
Glycine receptor betaZ subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  0.697
tmem130
Transmembrane protein 130.
   
  
 0.604
slc6a9
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.596
grik1b
Glutamate receptor, ionotropic, kainate 1b.
   
  
 0.573
slc6a5
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.570
polr2d
Polymerase (RNA) II (DNA directed) polypeptide D.
      
 0.560
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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