spire2 protein (Danio rerio) - STRING interaction network

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spire2

Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...] (730 aa)

Predicted Functional Partners:

fmn2a

0.850

fmn2b

0.836

def8

0.800

fmn1

0.750

ZNF276

0.722

vps9d1

0.675

fbxo33

0.661

gcat

0.609

pacrg

0.591

fybb

0.583

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ZNF276	def8	ENSDARP00000155751	ENSDARP00000132751	Zgc:158366.	Differentially-expressed in FDCP 8 homolog.	0.816
ZNF276	spire2	ENSDARP00000155751	ENSDARP00000031129	Zgc:158366.	Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...]	0.722
ZNF276	vps9d1	ENSDARP00000155751	ENSDARP00000117841	Zgc:158366.	VPS9 domain-containing 1.	0.825
def8	ZNF276	ENSDARP00000132751	ENSDARP00000155751	Differentially-expressed in FDCP 8 homolog.	Zgc:158366.	0.816
def8	spire2	ENSDARP00000132751	ENSDARP00000031129	Differentially-expressed in FDCP 8 homolog.	Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...]	0.800
def8	vps9d1	ENSDARP00000132751	ENSDARP00000117841	Differentially-expressed in FDCP 8 homolog.	VPS9 domain-containing 1.	0.788
fbxo33	pacrg	ENSDARP00000103689	ENSDARP00000106202	F-box protein 33.	PARK2 co-regulated.	0.871
fbxo33	spire2	ENSDARP00000103689	ENSDARP00000031129	F-box protein 33.	Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...]	0.661
fmn1	spire2	ENSDARP00000122153	ENSDARP00000031129	Formin 1.	Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...]	0.750
fmn2a	spire2	ENSDARP00000127786	ENSDARP00000031129	Formin 2a.	Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...]	0.850
fmn2b	spire2	ENSDARP00000148541	ENSDARP00000031129	Formin 2b.	Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...]	0.836
fybb	spire2	ENSDARP00000065673	ENSDARP00000031129	FYN-binding protein b.	Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...]	0.583
gcat	spire2	ENSDARP00000020361	ENSDARP00000031129	Glycine C-acetyltransferase.	Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...]	0.609
pacrg	fbxo33	ENSDARP00000106202	ENSDARP00000103689	PARK2 co-regulated.	F-box protein 33.	0.871
pacrg	spire2	ENSDARP00000106202	ENSDARP00000031129	PARK2 co-regulated.	Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...]	0.591
spire2	ZNF276	ENSDARP00000031129	ENSDARP00000155751	Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...]	Zgc:158366.	0.722
spire2	def8	ENSDARP00000031129	ENSDARP00000132751	Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...]	Differentially-expressed in FDCP 8 homolog.	0.800
spire2	fbxo33	ENSDARP00000031129	ENSDARP00000103689	Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...]	F-box protein 33.	0.661
spire2	fmn1	ENSDARP00000031129	ENSDARP00000122153	Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...]	Formin 1.	0.750
spire2	fmn2a	ENSDARP00000031129	ENSDARP00000127786	Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly o [...]	Formin 2a.	0.850

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