vangl2 protein (Danio rerio) - STRING interaction network

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vangl2

Vang-like protein 2; Plays a role in non-canonical Wnt/planar cell polarity (PCP) signaling to regulate convergent extension cell movements during gastrulation. Acts together with scrib and prickle1 and localizes prickle1 and dvl2/dsh to the plasma membrane. Has an overlapping role with kny during both convergent extension and eye development. In the eye, involved in establishing proper alignment of the anterior neural plate and midline cells expressing shha and shhb/twhh. Has indirect effects on a number of other developmental processes including notochord shape formation, neural prog [...] (526 aa)

Predicted Functional Partners:

prickle2a

0.999

prickle1a

0.999

prickle1b

0.999

prickle2b

0.999

dvl2

0.993

dvl1b

0.988

dvl3a

0.987

dvl3

0.986

celsr1a

0.969

tbx1

0.962

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
celsr1a	dvl1b	ENSDARP00000043736	ENSDARP00000094527	Cadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family.	Dishevelled segment polarity protein 1b.	0.862
celsr1a	dvl2	ENSDARP00000043736	ENSDARP00000021237	Cadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family.	Dishevelled segment polarity protein 2.	0.834
celsr1a	dvl3	ENSDARP00000043736	ENSDARP00000141947	Cadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family.	Dishevelled segment polarity protein 3b.	0.711
celsr1a	dvl3a	ENSDARP00000043736	ENSDARP00000088503	Cadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family.	Dishevelled segment polarity protein 3a.	0.696
celsr1a	prickle1a	ENSDARP00000043736	ENSDARP00000059513	Cadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family.	Prickle homolog 1a.	0.947
celsr1a	prickle1b	ENSDARP00000043736	ENSDARP00000118988	Cadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family.	Prickle homolog 1b.	0.896
celsr1a	prickle2a	ENSDARP00000043736	ENSDARP00000012600	Cadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family.	Prickle homolog 2a.	0.890
celsr1a	prickle2b	ENSDARP00000043736	ENSDARP00000135945	Cadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family.	Prickle homolog 2b.	0.898
celsr1a	tbx1	ENSDARP00000043736	ENSDARP00000040825	Cadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family.	T-box transcription factor TBX1; May act as a transcriptional factor. Acts cell autonomously in the pharyngeal mesendoderm and influences the development of neural crest-derived cartilages secondarily.	0.833
celsr1a	vangl2	ENSDARP00000043736	ENSDARP00000031546	Cadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family.	Vang-like protein 2; Plays a role in non-canonical Wnt/planar cell polarity (PCP) signaling to regulate convergent extension cell movements during gastrulation. Acts together with scrib and prickle1 and localizes prickle1 and dvl2/dsh to the plasma membrane. Has an overlapping role with kny during both convergent extension and eye development. In the eye, involved in establishing proper alignment of the anterior neural plate and midline cells expressing shha and shhb/twhh. Has indirect effects on a number of other developmental processes including notochord shape formation, neural prog [...]	0.969
dvl1b	celsr1a	ENSDARP00000094527	ENSDARP00000043736	Dishevelled segment polarity protein 1b.	Cadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family.	0.862
dvl1b	dvl2	ENSDARP00000094527	ENSDARP00000021237	Dishevelled segment polarity protein 1b.	Dishevelled segment polarity protein 2.	0.530
dvl1b	dvl3	ENSDARP00000094527	ENSDARP00000141947	Dishevelled segment polarity protein 1b.	Dishevelled segment polarity protein 3b.	0.525
dvl1b	prickle1a	ENSDARP00000094527	ENSDARP00000059513	Dishevelled segment polarity protein 1b.	Prickle homolog 1a.	0.927
dvl1b	prickle1b	ENSDARP00000094527	ENSDARP00000118988	Dishevelled segment polarity protein 1b.	Prickle homolog 1b.	0.916
dvl1b	prickle2a	ENSDARP00000094527	ENSDARP00000012600	Dishevelled segment polarity protein 1b.	Prickle homolog 2a.	0.918
dvl1b	prickle2b	ENSDARP00000094527	ENSDARP00000135945	Dishevelled segment polarity protein 1b.	Prickle homolog 2b.	0.920
dvl1b	tbx1	ENSDARP00000094527	ENSDARP00000040825	Dishevelled segment polarity protein 1b.	T-box transcription factor TBX1; May act as a transcriptional factor. Acts cell autonomously in the pharyngeal mesendoderm and influences the development of neural crest-derived cartilages secondarily.	0.559
dvl1b	vangl2	ENSDARP00000094527	ENSDARP00000031546	Dishevelled segment polarity protein 1b.	Vang-like protein 2; Plays a role in non-canonical Wnt/planar cell polarity (PCP) signaling to regulate convergent extension cell movements during gastrulation. Acts together with scrib and prickle1 and localizes prickle1 and dvl2/dsh to the plasma membrane. Has an overlapping role with kny during both convergent extension and eye development. In the eye, involved in establishing proper alignment of the anterior neural plate and midline cells expressing shha and shhb/twhh. Has indirect effects on a number of other developmental processes including notochord shape formation, neural prog [...]	0.988
dvl2	celsr1a	ENSDARP00000021237	ENSDARP00000043736	Dishevelled segment polarity protein 2.	Cadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family.	0.834

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