sgk1 protein (Danio rerio) - STRING interaction network

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sgk1

Serine/threonine-protein kinase Sgk1; Protein kinase that may play an important role in cellular stress response. May be involved in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion (By similarity); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (433 aa)

Predicted Functional Partners:

mtor

0.971

pdpk1b

0.957

pdpk1a

0.957

sgk2b

0.907

A3KQ53_DANRE

0.902

rictorb

0.848

foxo1a

0.847

foxo3a

0.812

mdm2

0.808

mlst8

0.783

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A3KQ53_DANRE	foxo1a	ENSDARP00000009591	ENSDARP00000134884	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O1-A; Transcriptional regulator of cell cycle arrest required for cellular stress responses (By similarity). May be involved in regulating cellular homeostasis in the eye.	0.753
A3KQ53_DANRE	foxo3a	ENSDARP00000009591	ENSDARP00000036177	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O3A.	0.761
A3KQ53_DANRE	mlst8	ENSDARP00000009591	ENSDARP00000118004	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Target of rapamycin complex subunit lst8.	0.507
A3KQ53_DANRE	mtor	ENSDARP00000009591	ENSDARP00000105458	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.971
A3KQ53_DANRE	pdpk1a	ENSDARP00000009591	ENSDARP00000093021	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	3-phosphoinositide-dependent protein kinase 1a.	0.957
A3KQ53_DANRE	pdpk1b	ENSDARP00000009591	ENSDARP00000019085	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	3-phosphoinositide-dependent protein kinase 1b.	0.956
A3KQ53_DANRE	rictorb	ENSDARP00000009591	ENSDARP00000118822	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	RPTOR-independent companion of MTOR, complex 2b.	0.565
A3KQ53_DANRE	sgk1	ENSDARP00000009591	ENSDARP00000031762	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase Sgk1; Protein kinase that may play an important role in cellular stress response. May be involved in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion (By similarity); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.902
A3KQ53_DANRE	sgk2b	ENSDARP00000009591	ENSDARP00000021458	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Serum/glucocorticoid-regulated kinase 2b; Belongs to the protein kinase superfamily.	0.903
foxo1a	A3KQ53_DANRE	ENSDARP00000134884	ENSDARP00000009591	Forkhead box protein O1-A; Transcriptional regulator of cell cycle arrest required for cellular stress responses (By similarity). May be involved in regulating cellular homeostasis in the eye.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.753
foxo1a	mdm2	ENSDARP00000134884	ENSDARP00000072320	Forkhead box protein O1-A; Transcriptional regulator of cell cycle arrest required for cellular stress responses (By similarity). May be involved in regulating cellular homeostasis in the eye.	E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.	0.720
foxo1a	pdpk1b	ENSDARP00000134884	ENSDARP00000019085	Forkhead box protein O1-A; Transcriptional regulator of cell cycle arrest required for cellular stress responses (By similarity). May be involved in regulating cellular homeostasis in the eye.	3-phosphoinositide-dependent protein kinase 1b.	0.440
foxo1a	sgk1	ENSDARP00000134884	ENSDARP00000031762	Forkhead box protein O1-A; Transcriptional regulator of cell cycle arrest required for cellular stress responses (By similarity). May be involved in regulating cellular homeostasis in the eye.	Serine/threonine-protein kinase Sgk1; Protein kinase that may play an important role in cellular stress response. May be involved in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion (By similarity); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.847
foxo1a	sgk2b	ENSDARP00000134884	ENSDARP00000021458	Forkhead box protein O1-A; Transcriptional regulator of cell cycle arrest required for cellular stress responses (By similarity). May be involved in regulating cellular homeostasis in the eye.	Serum/glucocorticoid-regulated kinase 2b; Belongs to the protein kinase superfamily.	0.723
foxo3a	A3KQ53_DANRE	ENSDARP00000036177	ENSDARP00000009591	Forkhead box O3A.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.761
foxo3a	mdm2	ENSDARP00000036177	ENSDARP00000072320	Forkhead box O3A.	E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.	0.538
foxo3a	mtor	ENSDARP00000036177	ENSDARP00000105458	Forkhead box O3A.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.400
foxo3a	sgk1	ENSDARP00000036177	ENSDARP00000031762	Forkhead box O3A.	Serine/threonine-protein kinase Sgk1; Protein kinase that may play an important role in cellular stress response. May be involved in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion (By similarity); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.812
foxo3a	sgk2b	ENSDARP00000036177	ENSDARP00000021458	Forkhead box O3A.	Serum/glucocorticoid-regulated kinase 2b; Belongs to the protein kinase superfamily.	0.695
mdm2	foxo1a	ENSDARP00000072320	ENSDARP00000134884	E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.	Forkhead box protein O1-A; Transcriptional regulator of cell cycle arrest required for cellular stress responses (By similarity). May be involved in regulating cellular homeostasis in the eye.	0.720

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