STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdcd5Programmed cell death 5. (128 aa)    
Predicted Functional Partners:
snrpe
Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
   
    0.898
rpl30
Ribosomal protein L30.
   
    0.867
rps19
Ribosomal protein S19.
  
    0.864
rpl35
60S ribosomal protein L35; Plays an essential role in early embryonic development. May act as a haploinsufficient tumor suppressor. Belongs to the universal ribosomal protein uL29 family.
   
    0.859
rpl23
60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
   
  
 0.859
rps28
40S ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family.
  
    0.855
rps3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
   
  
 0.852
rpl34
60S ribosomal protein L34; Component of the large ribosomal subunit.
   
    0.843
rpl32
Ribosomal protein L32.
   
  
 0.839
rps4x
40S ribosomal protein S4, X isoform; Belongs to the eukaryotic ribosomal protein eS4 family.
   
    0.824
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.