Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
il11raInterleukin 11 receptor alpha chain. (402 aa)    
Predicted Functional Partners:
il6st
Interleukin 6 signal transducer.
    
 0.991
csf3r
Colony-stimulating factor 3 receptor (granulocyte).
   
 0.970
il11a
Interleukin 11a.
     
 0.960
il12rb2l
Interleukin 12 receptor, beta 2a,-like.
    
 0.960
il11b
Interleukin 11b.
     
 0.928
il6
Interleukin 6 (interferon, beta 2).
     
 0.877
il15ra
Interleukin 15 receptor subunit alpha.
     
 0.831
il12rb2
Interleukin 12 receptor beta 2.a.
    
 0.702
il13ra2
Interleukin 13 receptor, alpha 2.
     
 0.661
lifrb
LIF receptor subunit alpha b.
    
 0.657
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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