Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
nol11Nucleolar protein 11-like; Ribosome biogenesis factor. May be required for both optimal rDNA transcription and pre-rRNA processing (By similarity). (708 aa)    
Predicted Functional Partners:
wdr43
WD repeat domain 43.
   
 
 0.996
utp4
Cirrhosis, autosomal recessive 1A (Cirhin).
   
 
 0.995
utp15
U3 small nucleolar RNA-associated protein 15 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA.
   
 
 0.984
nol7
Nucleolar protein 7.
    
 
 0.960
wdr75
WD repeat-containing protein 75; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I.
   
 
 0.957
heatr1
HEAT repeat-containing protein 1; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Required for cell survival in the CNS through its role in rRNA synthesis and processing.
   
 
 0.938
wdr12
Ribosome biogenesis protein wdr12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
   
  
 0.810
utp6
UTP6 small subunit processome component.
   
  
 0.794
fbl
Fibrillarin.
   
 
 0.751
golga4
Golgin A4.
   
   0.672
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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