| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ada | aox5 | ENSDARP00000005284 | ENSDARP00000134334 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Aldehyde oxidase alpha. | 0.687 |
| ada | aprt | ENSDARP00000005284 | ENSDARP00000124165 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Adenine phosphoribosyltransferase. | 0.950 |
| ada | dck | ENSDARP00000005284 | ENSDARP00000089270 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Deoxycytidine kinase. | 0.974 |
| ada | gda | ENSDARP00000005284 | ENSDARP00000010155 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.663 |
| ada | hprt1l | ENSDARP00000005284 | ENSDARP00000008019 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.461 |
| ada | nt5e | ENSDARP00000005284 | ENSDARP00000095510 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. | 0.973 |
| ada | pnp4a | ENSDARP00000005284 | ENSDARP00000032177 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.985 |
| aox5 | ada | ENSDARP00000134334 | ENSDARP00000005284 | Aldehyde oxidase alpha. | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.687 |
| aox5 | aprt | ENSDARP00000134334 | ENSDARP00000124165 | Aldehyde oxidase alpha. | Adenine phosphoribosyltransferase. | 0.822 |
| aox5 | gda | ENSDARP00000134334 | ENSDARP00000010155 | Aldehyde oxidase alpha. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.908 |
| aox5 | hprt1l | ENSDARP00000134334 | ENSDARP00000008019 | Aldehyde oxidase alpha. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.817 |
| aox5 | pnp4a | ENSDARP00000134334 | ENSDARP00000032177 | Aldehyde oxidase alpha. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.956 |
| aprt | ada | ENSDARP00000124165 | ENSDARP00000005284 | Adenine phosphoribosyltransferase. | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.950 |
| aprt | aox5 | ENSDARP00000124165 | ENSDARP00000134334 | Adenine phosphoribosyltransferase. | Aldehyde oxidase alpha. | 0.822 |
| aprt | dck | ENSDARP00000124165 | ENSDARP00000089270 | Adenine phosphoribosyltransferase. | Deoxycytidine kinase. | 0.558 |
| aprt | gda | ENSDARP00000124165 | ENSDARP00000010155 | Adenine phosphoribosyltransferase. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.578 |
| aprt | hprt1l | ENSDARP00000124165 | ENSDARP00000008019 | Adenine phosphoribosyltransferase. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.553 |
| aprt | naprt | ENSDARP00000124165 | ENSDARP00000035128 | Adenine phosphoribosyltransferase. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | 0.476 |
| aprt | nt5e | ENSDARP00000124165 | ENSDARP00000095510 | Adenine phosphoribosyltransferase. | 5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. | 0.962 |
| aprt | pnp4a | ENSDARP00000124165 | ENSDARP00000032177 | Adenine phosphoribosyltransferase. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.990 |
