Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
nvlNuclear VCP-like. (796 aa)    
Predicted Functional Partners:
wdr74
WD repeat domain 74.
   
 
 0.961
mtrex
Mtr4 exosome RNA helicase.
   
 
 0.952
pes
Pescadillo; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
   
 
 0.936
rpf2
Ribosome production factor 2 homolog.
   
 
 0.930
polr1a
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.926
ddx56
DEAD (Asp-Glu-Ala-Asp) box helicase 56.
   
 
 0.921
rbm28
RNA-binding motif protein 28.
   
  
 0.918
mak16
Protein MAK16 homolog; Plays an essential role in early embryonic development.
   
 
 0.904
nifk
MKI67 FHA domain-interacting nucleolar phosphoprotein; Plays an essential role in early embryonic development.
   
 
 0.900
UTP14C
Si:dkey-251i10.3.
   
  
 0.896
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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