Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tspan36Tetraspanin-36; Plays a role in migration and segregation of pigment cells (melanophores and xanthophores). Contributes to pigment stripe patterning in the epidermis; Belongs to the tetraspanin (TM4SF) family. (243 aa)    
Predicted Functional Partners:
jac4
Jacalin 4.
      
 0.713
LOC564481
Hypothetical protein LOC564481.
      
 0.713
ENSDARP00000142590
Si:dkeyp-32g11.8.
      
 0.713
LOC564660
Hypothetical protein LOC564660.
      
 0.713
gadd45gip1
Growth arrest and DNA-damage-inducible, gamma-interacting protein 1.
      
 0.649
siva1
SIVA1, apoptosis-inducing factor.
      
 0.633
phf21ab
PHD finger protein 21Ab.
      
 0.625
jac2
Jacalin 2.
      
 0.596
jac3
Jacalin 3.
      
 0.596
aep1
Aerolysin-like protein; Pore-forming protein which might play a role in host defense. Exists as an antiparallel dimer in solution. Can also assemble into an octameric pore-like structure spanning the cell membrane. Oligomerization may be triggered by binding of the jacalin-type lectin domain to high-mannose cell-surface proteoglycans, and also requires a low pH environment. In vitro, shows high binding affinity for S.cerevisiae mannan and human HIV virus glycoprotein gp120.
      
 0.594
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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