Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
pvalb4Pvalb4 protein; Belongs to the parvalbumin family. (109 aa)    
Predicted Functional Partners:
ENSDARP00000141227
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 
 0.730
F1QHP3_DANRE
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 
 0.727
LOC100334697
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 
 0.693
ftr86
FinTRIM family, member 86.
   
 
 0.692
ponzr4
Plac8 onzin-related protein 4.
    
 
 0.691
tnnt2d
Troponin T2d, cardiac.
   
 0.690
ces2b-2
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 
 0.677
ponzr3
Plac8 onzin-related protein 3.
    
 
 0.673
wu:fk65c09
Wu:fk65c09; Belongs to the intermediate filament family.
    
 
 0.670
ak1
Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
   
 0.653
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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