Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dpf3Zinc finger protein DPF3; Muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Specifically binds acetylated lysines on histone 3 and 4. In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex) and may play a role in neural development (By similarity). Plays an essential role in heart and skeletal [...] (391 aa)    
Predicted Functional Partners:
dpf1
D4, zinc and double PHD fingers family 1.
  
 
0.994
smarcd2
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily d, member 2.
   
 0.989
pbrm1
Polybromo 1.
    
 0.988
actl6b
Actin-like 6B; Belongs to the actin family.
   
 0.985
smarcc2
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily c, member 2.
    
 0.984
smarcb1a
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1-A; Involved in chromatin-remodeling. Core component of the BAF (SWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex) and may play a role in neural development (By similarity).
   
 0.981
smarcd1
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily d, member 1.
   
 0.978
smarcc1a
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily c, member 1a.
   
 0.975
smarcc1b
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily c, member 1b.
    
 0.969
arid1aa
AT-rich interactive domain 1Aa (SWI-like).
   
 0.967
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.