Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
snx4Sorting nexin 4. (434 aa)    
Predicted Functional Partners:
snx1a
Sorting nexin 1a.
   
 
 0.982
vti1b
Vesicle transport through interaction with t-SNAREs homolog 1B (Yeast).
   
 
 0.957
snx2
Sorting nexin 2.
   
 
 0.957
snx7
Sorting nexin 7.
  
0.946
vamp8
Vesicle-associated membrane protein 8 (Endobrevin).
    
 0.936
stx8
Stx8 protein.
   
 0.934
stx7l
Syntaxin 7-like; Belongs to the syntaxin family.
   
 0.930
sec22bb
Vesicle-trafficking protein SEC22b-B; SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
   
 
 0.930
vamp2
Vesicle-associated membrane protein 2.
    
 0.929
vamp1
Vesicle-associated membrane protein 1.
    
 0.929
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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