Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
col21a1Collagen, type XXI, alpha 1. (717 aa)    
Predicted Functional Partners:
hmgcll1
3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic; Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3- methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues.
      
 0.799
lrrc75ba
Leucine-rich repeat-containing 75Ba.
      
 0.792
F6NKU7_DANRE
Si:dkey-76b14.2.
      
 0.775
phykpl
5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
      
 0.719
cfap299
Cilia- and flagella-associated protein 299; May be involved in spermatogenesis.
    
 
 0.697
itgb1bp1
Integrin beta-1-binding protein 1.
      
 0.594
shroom4
Shroom family member 4.
    
 
 0.590
hpcal4
Hippocalcin-like 4.
    
 
 0.582
ENSDARP00000156938
Si:ch211-212d10.1; Belongs to the peptidase S1 family.
    
 0.579
EPB41L2
Si:ch73-18b11.1.
      
 0.575
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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