Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
abcg2cATP-binding cassette, sub-family G (WHITE), member 2c. (634 aa)    
Predicted Functional Partners:
abcg2d
ATP-binding cassette transporter sub-family G member 2d.
  
  
0.738
abcg5
ATP-binding cassette, sub-family G (WHITE), member 5.
   
 0.722
abcg2a
ATP-binding cassette, sub-family G (WHITE), member 2a.
     
  0.695
trip12
E3 ubiquitin-protein ligase TRIP12; E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins. Acts as a key regulator of DNA damage response by acting as a suppressor of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of 'Lys-63'-linked histone H2A and H2AX at DNA damage sites, thereby acting as a guard against excessive spr [...]
     
 0.603
tlcd4a
TLC domain-containing 4a.
      
 0.572
abcg4b
ATP-binding cassette, sub-family G (WHITE), member 4b.
  
  
0.551
abcf2a
ATP-binding cassette, sub-family F (GCN20), member 2a.
    
 
 0.550
abcg4a
ATP-binding cassette, sub-family G (WHITE), member 4a.
  
  
0.549
abcc13
ATP-binding cassette, sub-family C (CFTR/MRP), member 13.
    
 0.532
abcg1
ATP-binding cassette, sub-family G (WHITE), member 1.
  
  
0.487
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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