Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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[Homology]
Score
iscubIron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (164 aa)    
Predicted Functional Partners:
nfs1
NFS1 nitrogen fixation 1 (S. cerevisiae).
 
 0.989
scly
Selenocysteine lyase.
  
 0.960
drll.2
Draculin-like, tandem duplicate 1.
    
 
 0.953
thyn1
Thymocyte nuclear protein 1; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
     
 0.929
zgc:64022
Zgc:64022.
      
 0.886
fxn
Frataxin.
    
 
 0.862
hspa9
Heat shock protein 9; Belongs to the heat shock protein 70 family.
  
 
 0.846
fdx2
Ferredoxin-2, mitochondrial; Essential for heme A and Fe/S protein biosynthesis.
 
 
 0.820
isca1
Iron-sulfur cluster assembly 1 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. Belongs to the HesB/IscA family.
  
  
 0.814
isca2
Iron-sulfur cluster assembly 2.
  
  
 0.813
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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