STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hddc3Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1; ppGpp hydrolyzing enzyme involved in starvation response. (180 aa)    
Predicted Functional Partners:
mrpl15
39S ribosomal protein L15, mitochondrial; Belongs to the universal ribosomal protein uL15 family.
   
 
 0.972
rpl11
60S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.
    
   0.970
nme2a
Nucleoside diphosphate kinase.
    
 0.953
nme7
Nucleoside diphosphate kinase 7; Belongs to the NDK family.
  
 
 0.953
nme6
Nucleoside diphosphate kinase 6; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.953
nme4
Nucleoside diphosphate kinase.
    
 0.953
nme3
Nucleoside diphosphate kinase.
    
 0.953
nme2b.2
Nucleoside diphosphate kinase.
    
 0.953
ak9
Adenylate kinase 9.
  
 
  0.942
mrps9
Mitochondrial ribosomal protein S9.
  
 
 0.941
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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