Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmem134Transmembrane protein 134. (206 aa)    
Predicted Functional Partners:
ubxn4
UBX domain protein 4.
    
   0.740
fam216a
Uncharacterized protein.
      
 0.702
rnf170
E3 ubiquitin-protein ligase RNF170; E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor (ITPR) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR turnover in resting cells.
      
 0.674
slc25a27
Solute carrier family 25 member 27; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.672
mrps2
Mitochondrial ribosomal protein S2.
   
  
 0.667
CABP4
Si:cabz01076231.1.
      
 0.646
ppm1e
Protein phosphatase, Mg2+/Mn2+-dependent, 1E.
      
 0.645
slc8b1
Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.637
A5WW23_DANRE
Si:ch211-39k3.2.
      
 0.634
serf2
Small EDRK-rich factor 2.
      
 0.634
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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