Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rprmbProtein reprimo B; May be involved in the regulation of p53-dependent G2 arrest of the cell cycle; Belongs to the reprimo family. (102 aa)    
Predicted Functional Partners:
rprml
Reprimo-like protein.
     
  0.871
rprm3
Reprimo, TP53-dependent G2 arrest mediator homolog 3.
     
  0.811
arl6ip6
ADP-ribosylation factor-like 6-interacting protein 6.
      
 0.685
wdr20a
WD repeat domain 20a.
      
 0.683
plekhf2
Pleckstrin homology domain-containing family F member 2; May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis.
      
 0.660
plekhh2
Pleckstrin homology domain-containing, family H (with MyTH4 domain) member 2.
      
 0.660
npb
Neuropeptide B.
      
 0.630
kcnj3b
Potassium inwardly rectifying channel subfamily J member 3b.
      
 0.610
kcnj19b
Potassium inwardly rectifying channel subfamily J member 19b.
      
 0.609
cd164l2
CD164 sialomucin-like 2.
      
 0.594
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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