STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rab5cRAB5C, member RAS oncogene family. (221 aa)    
Predicted Functional Partners:
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
   
 0.970
eea1
Early endosome antigen 1.
    
 0.951
rabgef1
RAB guanine nucleotide exchange factor (GEF) 1.
   
 0.942
rabgef1l
RAB guanine nucleotide exchange factor (GEF) 1,-like.
   
 
 0.889
rabep1
Rabaptin, RAB GTPase-binding effector protein 1.
   
 0.863
appl1
HESX homeobox 1.
   
 
 0.816
gdi2
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
   
 0.802
gapvd1
GTPase-activating protein and VPS9 domains 1.
    
 0.795
gdi1
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
   
 0.787
rbsn
Rabenosyn, RAB effector.
   
 
 0.758
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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