Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spon1bSpondin 1b. (804 aa)    
Predicted Functional Partners:
rps27.2
40S ribosomal protein S27.
      
 0.735
plppr3a
Phospholipid phosphatase-related 3a.
      
 0.596
tspan7b
Tetraspanin.
   
  
 0.587
map3k15
Mitogen-activated protein kinase kinase kinase 15.
      
 0.577
vstm2l
V-set and transmembrane domain-containing 2-like.
      
 0.571
ppdpfb
Pancreatic progenitor cell differentiation and proliferation factor B; Probable regulator of exocrine pancreas development.
      
 0.566
slc29a1a
Solute carrier family 29 member 1a.
      
 0.558
ppdpfa
Pancreatic progenitor cell differentiation and proliferation factor A; Probable regulator of exocrine pancreas development.
      
 0.503
gga3a
Golgi-associated, gamma adaptin ear-containing, ARF-binding protein 3a.
      
 0.492
ift22
Intraflagellar transport protein 22 homolog; Belongs to the small GTPase superfamily. Rab family.
      
 0.490
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (24%) [HD]