Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mospd2Motile sperm domain-containing 2. (526 aa)    
Predicted Functional Partners:
stard3
StAR-related lipid transfer protein 3; Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes. Creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum. Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes.
   
 
 0.938
arrdc1a
Arrestin domain-containing 1a.
    
 
 0.801
rftn2
Raftlin family member 2.
      
 0.800
stard3nl
STARD3 N-terminal-like.
   
 
 0.767
top1mt-2
DNA topoisomerase I mitochondrial.
    
 
 0.762
osbp
Oxysterol-binding protein; Belongs to the OSBP family.
    
 
 0.750
gpn3
GPN-loop GTPase 3; Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.
    
 
 0.744
mospd1
Motile sperm domain-containing 1.
   
 
 0.739
map3k5
Mitogen-activated protein kinase kinase kinase 5.
    
   0.729
ENSDARP00000146561
Si:ch211-1i11.3.
    
   0.729
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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