Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OTOP1Otopetrin 1. (587 aa)    
Predicted Functional Partners:
oc90
Otoconin 90.
   
  
 0.928
otol1b
Otolin 1b.
      
 0.880
tecta
Tectorin alpha.
      
 0.816
otol1a
Otolin-1-A; Collagen-like protein, which provides an organic scaffold for otoliths onto the sensory epithelium of the inner ear. Acts as a scaffold for biomineralization by sequestering calcium ; Belongs to the OTOL1 family.
   
  
 0.809
otomp
Otolith matrix protein 1; Required for normal otolith growth and deposition of otolin-1 in the otolith.
      
 0.807
rftn2
Raftlin family member 2.
   
  
 0.783
arrdc1a
Arrestin domain-containing 1a.
      
 0.780
sparcl2
SPARC-like 2.
      
 0.759
calhm1
Calcium homeostasis modulator 1.
   
  
 0.748
otog
Otogelin.
   
  
 0.727
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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