| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apaf1 | bcl2a | ENSDARP00000008347 | ENSDARP00000120749 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | B-cell leukemia/lymphoma 2. | 0.955 |
| apaf1 | bcl2l1 | ENSDARP00000008347 | ENSDARP00000027919 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Bcl-XL-like protein 1. | 0.987 |
| apaf1 | casp3a | ENSDARP00000008347 | ENSDARP00000006831 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | 0.988 |
| apaf1 | casp3b | ENSDARP00000008347 | ENSDARP00000071815 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. | 0.981 |
| apaf1 | casp9 | ENSDARP00000008347 | ENSDARP00000047019 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | 0.999 |
| apaf1 | cyc1 | ENSDARP00000008347 | ENSDARP00000055503 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Cytochrome c-1. | 0.548 |
| apaf1 | cycsb | ENSDARP00000008347 | ENSDARP00000034555 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | 0.999 |
| apaf1 | uqcrb | ENSDARP00000008347 | ENSDARP00000011797 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. | 0.546 |
| apaf1 | uqcrfs1 | ENSDARP00000008347 | ENSDARP00000011707 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.496 |
| bcl2a | apaf1 | ENSDARP00000120749 | ENSDARP00000008347 | B-cell leukemia/lymphoma 2. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | 0.955 |
| bcl2a | bcl2l1 | ENSDARP00000120749 | ENSDARP00000027919 | B-cell leukemia/lymphoma 2. | Bcl-XL-like protein 1. | 0.976 |
| bcl2a | casp3a | ENSDARP00000120749 | ENSDARP00000006831 | B-cell leukemia/lymphoma 2. | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | 0.994 |
| bcl2a | casp3b | ENSDARP00000120749 | ENSDARP00000071815 | B-cell leukemia/lymphoma 2. | Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. | 0.994 |
| bcl2a | casp9 | ENSDARP00000120749 | ENSDARP00000047019 | B-cell leukemia/lymphoma 2. | Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | 0.991 |
| bcl2a | cycsb | ENSDARP00000120749 | ENSDARP00000034555 | B-cell leukemia/lymphoma 2. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | 0.997 |
| bcl2l1 | apaf1 | ENSDARP00000027919 | ENSDARP00000008347 | Bcl-XL-like protein 1. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity). | 0.987 |
| bcl2l1 | bcl2a | ENSDARP00000027919 | ENSDARP00000120749 | Bcl-XL-like protein 1. | B-cell leukemia/lymphoma 2. | 0.976 |
| bcl2l1 | casp3a | ENSDARP00000027919 | ENSDARP00000006831 | Bcl-XL-like protein 1. | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | 0.959 |
| bcl2l1 | casp3b | ENSDARP00000027919 | ENSDARP00000071815 | Bcl-XL-like protein 1. | Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. | 0.957 |
| bcl2l1 | casp9 | ENSDARP00000027919 | ENSDARP00000047019 | Bcl-XL-like protein 1. | Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | 0.997 |