Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trim63aTripartite motif-containing 63a. (345 aa)    
Predicted Functional Partners:
fbxo32
F-box protein 32.
      
 0.923
fbxo30a
F-box protein 30a.
   
  
 0.738
fbxo25
F-box only protein 25.
      
 0.737
capn3a
Calpain 3a, (p94); Belongs to the peptidase C2 family.
    
 
 0.684
myog
Myogenin.
   
  
 0.642
trim55b
Tripartite motif-containing 55b.
  
 
0.641
sqstm1
Sequestosome 1.
    
 
 0.641
trim54
Tripartite motif-containing 54.
     
  0.639
MANEAL
Glycoprotein endo-alpha-1,2-mannosidase-like protein.
     
 0.609
myod1
Myoblast determination protein 1 homolog; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
   
 
 0.603
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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