Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tpm4aTropomyosin 4a; Belongs to the tropomyosin family. (284 aa)    
Predicted Functional Partners:
tnnt2e
Novel slow skeletal troponin T family protein.
   
 0.943
actc1c
Actin alpha cardiac muscle 1a.
   
 0.929
tnnt2a
Troponin T type 2a (cardiac).
   
 0.885
actc1a
Actin, alpha, cardiac muscle 1a.
   
 0.882
tnni1b
Troponin I type 1b (skeletal, slow).
   
 0.844
zgc:86709
Novel actin protein.
   
 0.823
tnnt2b
Troponin T type 2b (cardiac).
   
 0.817
tnnt2d
Troponin T2d, cardiac.
   
 0.809
actc1b
Actin, alpha 1, skeletal muscle.
   
 0.799
tnni4a
Troponin I4a.
   
 0.799
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.