Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
arhgap1Rho GTPase-activating protein 1. (434 aa)    
Predicted Functional Partners:
cdc42l2
Cell division cycle 42-like 2.
    
 0.966
cdc42
Cell division cycle 42.
    
 
 0.960
rhocb
Rho-related GTP-binding protein RhoA-D; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
    
 0.832
rhoaa
Rho-related GTP-binding protein RhoA-A; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
    
 0.832
rhoac
Rho-related GTP-binding protein RhoA-C; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
    
 0.799
cdc42l
Cell division cycle 42,-like.
    
 
 0.794
atcayb
ATCAY kinesin light chain-interacting caytaxin b.
    
 
 0.782
retreg2
Family with sequence similarity 134, member A.
      
 0.736
rhoab
Rho-related GTP-binding protein RhoA-B; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
    
 
 0.678
rhoca
Ras homolog gene family, member Ae.
    
 
 0.678
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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