STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arhgap1Rho GTPase-activating protein 1. (434 aa)    
Predicted Functional Partners:
cdc42l2
Cell division cycle 42-like 2.
    
 0.957
cdc42
Cell division cycle 42.
    
 
 0.947
smpdl3a
Acid sphingomyelinase-like phosphodiesterase.
      
 0.836
retreg2
Family with sequence similarity 134, member A.
   
  
 0.808
rhocb
Rho-related GTP-binding protein RhoA-D; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
   
 0.787
rhoaa
Rho-related GTP-binding protein RhoA-A; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
    
 0.787
cdc42l
Cell division cycle 42,-like.
    
 
 0.775
rhoac
Rho-related GTP-binding protein RhoA-C; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
   
 0.746
vwde
Von Willebrand factor D and EGF domains.
    
 
 0.724
rhof
Ras homolog gene family, member F.
    
 0.693
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.