pnx protein (Danio rerio) - STRING interaction network

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pnx

Homeobox protein pnx; Transcriptional repressor. Activity as a repressor is enhanced by binding to the corepressor tle3a. (182 aa)

Predicted Functional Partners:

tle3a

0.639

neurog1

0.448

elavl3

0.443

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
elavl3	neurog1	ENSDARP00000030680	ENSDARP00000073024	ELAV-like protein; Belongs to the RRM elav family.	Neurogenin-1; Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon-Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specificati [...]	0.887
elavl3	pnx	ENSDARP00000030680	ENSDARP00000034835	ELAV-like protein; Belongs to the RRM elav family.	Homeobox protein pnx; Transcriptional repressor. Activity as a repressor is enhanced by binding to the corepressor tle3a.	0.443
neurog1	elavl3	ENSDARP00000073024	ENSDARP00000030680	Neurogenin-1; Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon-Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specificati [...]	ELAV-like protein; Belongs to the RRM elav family.	0.887
neurog1	pnx	ENSDARP00000073024	ENSDARP00000034835	Neurogenin-1; Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon-Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specificati [...]	Homeobox protein pnx; Transcriptional repressor. Activity as a repressor is enhanced by binding to the corepressor tle3a.	0.448
neurog1	tle3a	ENSDARP00000073024	ENSDARP00000045678	Neurogenin-1; Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon-Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specificati [...]	Transducin-like enhancer protein 3-A; Transcriptional corepressor that binds to a number of transcription factors. Enhances the transcriptional repression activity of pnx; Belongs to the WD repeat Groucho/TLE family.	0.401
pnx	elavl3	ENSDARP00000034835	ENSDARP00000030680	Homeobox protein pnx; Transcriptional repressor. Activity as a repressor is enhanced by binding to the corepressor tle3a.	ELAV-like protein; Belongs to the RRM elav family.	0.443
pnx	neurog1	ENSDARP00000034835	ENSDARP00000073024	Homeobox protein pnx; Transcriptional repressor. Activity as a repressor is enhanced by binding to the corepressor tle3a.	Neurogenin-1; Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon-Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specificati [...]	0.448
pnx	tle3a	ENSDARP00000034835	ENSDARP00000045678	Homeobox protein pnx; Transcriptional repressor. Activity as a repressor is enhanced by binding to the corepressor tle3a.	Transducin-like enhancer protein 3-A; Transcriptional corepressor that binds to a number of transcription factors. Enhances the transcriptional repression activity of pnx; Belongs to the WD repeat Groucho/TLE family.	0.639
tle3a	neurog1	ENSDARP00000045678	ENSDARP00000073024	Transducin-like enhancer protein 3-A; Transcriptional corepressor that binds to a number of transcription factors. Enhances the transcriptional repression activity of pnx; Belongs to the WD repeat Groucho/TLE family.	Neurogenin-1; Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon-Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specificati [...]	0.401
tle3a	pnx	ENSDARP00000045678	ENSDARP00000034835	Transducin-like enhancer protein 3-A; Transcriptional corepressor that binds to a number of transcription factors. Enhances the transcriptional repression activity of pnx; Belongs to the WD repeat Groucho/TLE family.	Homeobox protein pnx; Transcriptional repressor. Activity as a repressor is enhanced by binding to the corepressor tle3a.	0.639

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