STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slc48a1bHeme transporter hrg1-A; Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment. (144 aa)    
Predicted Functional Partners:
K7DYM1_DANRE
Si:ch211-201o1.1.
      
 0.860
slc7a6os
Probable RNA polymerase II nuclear localization protein SLC7A6OS; Directs RNA polymerase II nuclear import.
      
 0.762
slc35f2
Solute carrier family 35 member F2.
   
  
 0.675
alas2
5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
      
 0.645
slc25a46
Solute carrier family 25 member 46; May play a role in mitochondrial dynamics by controlling mitochondrial membrane fission.
   
  
 0.571
hmox2b
Heme oxygenase 2b.
      
 0.571
slc26a11
Solute carrier family 26 member 11.
      
 0.550
abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5.
      
 0.544
alas1
5-aminolevulinate synthase.
      
 0.540
slc9a8
Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
   
  
 0.523
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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