Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
slc48a1bHeme transporter hrg1-A; Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment. (144 aa)    
Predicted Functional Partners:
K7DYM1_DANRE
Si:ch211-201o1.1.
      
 0.876
slc7a8a
Solute carrier family 7 member 8a.
      
 0.719
slc7a6os
Probable RNA polymerase II nuclear localization protein SLC7A6OS; Directs RNA polymerase II nuclear import.
      
 0.694
slc35f2
Solute carrier family 35 member F2.
   
  
 0.600
alas2
5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
      
 0.590
slc25a38a
Mitochondrial glycine transporter A; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
      
 0.589
hmox2b
Heme oxygenase 2b.
      
 0.561
slc26a11
Solute carrier family 26 member 11.
      
 0.558
abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5.
      
 0.552
slc7a4
Solute carrier family 7 member 4.
      
 0.550
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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