node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
akt1 | gsk3ba | ENSDARP00000131294 | ENSDARP00000027785 | Non-specific serine/threonine protein kinase. | Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. | 0.943 |
akt1 | rheb | ENSDARP00000131294 | ENSDARP00000107964 | Non-specific serine/threonine protein kinase. | Ras homolog, mTORC1-binding. | 0.469 |
akt1 | rhebl1 | ENSDARP00000131294 | ENSDARP00000057222 | Non-specific serine/threonine protein kinase. | Ras homolog, mTORC1-binding-like 1. | 0.469 |
akt1 | tbc1d7 | ENSDARP00000131294 | ENSDARP00000040264 | Non-specific serine/threonine protein kinase. | TBC1 domain family member 7; Component of the TSC-TBC complex, that contains tbc1d7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward rheb in response to alterations in specific cellular growth conditions. The small GTPase rheb is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB (By similarity). | 0.730 |
akt1 | tsc1a | ENSDARP00000131294 | ENSDARP00000035073 | Non-specific serine/threonine protein kinase. | TSC complex subunit 1a. | 0.945 |
akt1 | tsc2 | ENSDARP00000131294 | ENSDARP00000131915 | Non-specific serine/threonine protein kinase. | TSC complex subunit 2. | 0.926 |
akt2 | akt3b | ENSDARP00000023119 | ENSDARP00000111940 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.753 |
akt2 | gsk3ba | ENSDARP00000023119 | ENSDARP00000027785 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. | 0.946 |
akt2 | rheb | ENSDARP00000023119 | ENSDARP00000107964 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Ras homolog, mTORC1-binding. | 0.493 |
akt2 | rhebl1 | ENSDARP00000023119 | ENSDARP00000057222 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Ras homolog, mTORC1-binding-like 1. | 0.493 |
akt2 | tbc1d7 | ENSDARP00000023119 | ENSDARP00000040264 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | TBC1 domain family member 7; Component of the TSC-TBC complex, that contains tbc1d7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward rheb in response to alterations in specific cellular growth conditions. The small GTPase rheb is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB (By similarity). | 0.730 |
akt2 | tsc1a | ENSDARP00000023119 | ENSDARP00000035073 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | TSC complex subunit 1a. | 0.938 |
akt2 | tsc2 | ENSDARP00000023119 | ENSDARP00000131915 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | TSC complex subunit 2. | 0.957 |
akt2l | gsk3ba | ENSDARP00000140634 | ENSDARP00000027785 | V-akt murine thymoma viral oncogene homolog 2,-like. | Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. | 0.935 |
akt2l | tbc1d7 | ENSDARP00000140634 | ENSDARP00000040264 | V-akt murine thymoma viral oncogene homolog 2,-like. | TBC1 domain family member 7; Component of the TSC-TBC complex, that contains tbc1d7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward rheb in response to alterations in specific cellular growth conditions. The small GTPase rheb is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB (By similarity). | 0.730 |
akt2l | tsc1a | ENSDARP00000140634 | ENSDARP00000035073 | V-akt murine thymoma viral oncogene homolog 2,-like. | TSC complex subunit 1a. | 0.941 |
akt2l | tsc2 | ENSDARP00000140634 | ENSDARP00000131915 | V-akt murine thymoma viral oncogene homolog 2,-like. | TSC complex subunit 2. | 0.926 |
akt3a | gsk3ba | ENSDARP00000139879 | ENSDARP00000027785 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. | 0.942 |
akt3a | rheb | ENSDARP00000139879 | ENSDARP00000107964 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Ras homolog, mTORC1-binding. | 0.459 |
akt3a | rhebl1 | ENSDARP00000139879 | ENSDARP00000057222 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Ras homolog, mTORC1-binding-like 1. | 0.493 |