Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
gstk1Glutathione S-transferase kappa. (229 aa)    
Predicted Functional Partners:
gstt1a
Glutathione S-transferase theta 1a; Belongs to the GST superfamily.
   
 0.917
ephx1
Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.
   
 
 0.880
prdx6
Peroxiredoxin 6.
   
 0.878
gsr
Glutathione reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
   
 
 0.865
aldh3b1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
 0.851
gstt1b
Glutathione S-transferase theta 1b.
   
 0.846
gss
Glutathione synthetase.
   
 
 0.846
cyp1b1
Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
    
 0.838
gsto2
Glutathione S-transferase omega 2.
   
 
 0.829
gpx1a
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 0.820
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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