node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
isoc1 | naprt | ENSDARP00000078713 | ENSDARP00000035128 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | 0.944 |
isoc1 | nmnat1 | ENSDARP00000078713 | ENSDARP00000120270 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Nicotinamide-nucleotide adenylyltransferase. | 0.590 |
isoc1 | nmnat2 | ENSDARP00000078713 | ENSDARP00000004144 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; Nicotinamide/nicotinate-nucleotide adenylyltransferase that acts as an axon maintenance factor (By similarity). Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NaAD as substrates and degrades nicotinic acid adenine dinucleotide phosp [...] | 0.590 |
isoc1 | nmnat3 | ENSDARP00000078713 | ENSDARP00000102719 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Nicotinamide-nucleotide adenylyltransferase. | 0.590 |
isoc2 | naprt | ENSDARP00000022030 | ENSDARP00000035128 | Isochorismatase domain-containing protein 2; Belongs to the isochorismatase family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | 0.944 |
isoc2 | nmnat1 | ENSDARP00000022030 | ENSDARP00000120270 | Isochorismatase domain-containing protein 2; Belongs to the isochorismatase family. | Nicotinamide-nucleotide adenylyltransferase. | 0.590 |
isoc2 | nmnat2 | ENSDARP00000022030 | ENSDARP00000004144 | Isochorismatase domain-containing protein 2; Belongs to the isochorismatase family. | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; Nicotinamide/nicotinate-nucleotide adenylyltransferase that acts as an axon maintenance factor (By similarity). Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NaAD as substrates and degrades nicotinic acid adenine dinucleotide phosp [...] | 0.590 |
isoc2 | nmnat3 | ENSDARP00000022030 | ENSDARP00000102719 | Isochorismatase domain-containing protein 2; Belongs to the isochorismatase family. | Nicotinamide-nucleotide adenylyltransferase. | 0.590 |
mibp | mibp2 | ENSDARP00000137169 | ENSDARP00000134727 | Muscle-specific beta 1 integrin-binding protein. | Muscle-specific beta 1 integrin-binding protein 2. | 0.903 |
mibp | naprt | ENSDARP00000137169 | ENSDARP00000035128 | Muscle-specific beta 1 integrin-binding protein. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | 0.939 |
mibp | nmnat1 | ENSDARP00000137169 | ENSDARP00000120270 | Muscle-specific beta 1 integrin-binding protein. | Nicotinamide-nucleotide adenylyltransferase. | 0.931 |
mibp | nmnat2 | ENSDARP00000137169 | ENSDARP00000004144 | Muscle-specific beta 1 integrin-binding protein. | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; Nicotinamide/nicotinate-nucleotide adenylyltransferase that acts as an axon maintenance factor (By similarity). Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NaAD as substrates and degrades nicotinic acid adenine dinucleotide phosp [...] | 0.931 |
mibp | nmnat3 | ENSDARP00000137169 | ENSDARP00000102719 | Muscle-specific beta 1 integrin-binding protein. | Nicotinamide-nucleotide adenylyltransferase. | 0.931 |
mibp | nmrk1 | ENSDARP00000137169 | ENSDARP00000055258 | Muscle-specific beta 1 integrin-binding protein. | Nicotinamide riboside kinase 1. | 0.902 |
mibp | nudt12 | ENSDARP00000137169 | ENSDARP00000139063 | Muscle-specific beta 1 integrin-binding protein. | Nudix (nucleoside diphosphate-linked moiety X)-type motif 12. | 0.904 |
mibp2 | mibp | ENSDARP00000134727 | ENSDARP00000137169 | Muscle-specific beta 1 integrin-binding protein 2. | Muscle-specific beta 1 integrin-binding protein. | 0.903 |
mibp2 | naprt | ENSDARP00000134727 | ENSDARP00000035128 | Muscle-specific beta 1 integrin-binding protein 2. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | 0.947 |
mibp2 | nmnat1 | ENSDARP00000134727 | ENSDARP00000120270 | Muscle-specific beta 1 integrin-binding protein 2. | Nicotinamide-nucleotide adenylyltransferase. | 0.931 |
mibp2 | nmnat2 | ENSDARP00000134727 | ENSDARP00000004144 | Muscle-specific beta 1 integrin-binding protein 2. | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; Nicotinamide/nicotinate-nucleotide adenylyltransferase that acts as an axon maintenance factor (By similarity). Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NaAD as substrates and degrades nicotinic acid adenine dinucleotide phosp [...] | 0.931 |
mibp2 | nmnat3 | ENSDARP00000134727 | ENSDARP00000102719 | Muscle-specific beta 1 integrin-binding protein 2. | Nicotinamide-nucleotide adenylyltransferase. | 0.931 |