| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| caspb | cela1.4 | ENSDARP00000068268 | ENSDARP00000035387 | Caspase b subunit p10; Thiol protease which cleaves IL-1 beta (il1b), releasing the mature cytokine which is involved in a variety of inflammatory processes, and mediates apoptosis. Component of the NLRP1 inflammasome, which plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, recruited to the NLRP1 inflammasome in its precursor form following the recruitment of caspase caspa. Its subsequent activation causes the cleavage of the midformed pro-il1b and results in il1b maturation and secretion in the extracellular milieu. [...] | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | 0.604 |
| caspb | gsdmea | ENSDARP00000068268 | ENSDARP00000125872 | Caspase b subunit p10; Thiol protease which cleaves IL-1 beta (il1b), releasing the mature cytokine which is involved in a variety of inflammatory processes, and mediates apoptosis. Component of the NLRP1 inflammasome, which plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, recruited to the NLRP1 inflammasome in its precursor form following the recruitment of caspase caspa. Its subsequent activation causes the cleavage of the midformed pro-il1b and results in il1b maturation and secretion in the extracellular milieu. [...] | Gasdermin Ea. | 0.960 |
| caspb | gsdmeb | ENSDARP00000068268 | ENSDARP00000059251 | Caspase b subunit p10; Thiol protease which cleaves IL-1 beta (il1b), releasing the mature cytokine which is involved in a variety of inflammatory processes, and mediates apoptosis. Component of the NLRP1 inflammasome, which plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, recruited to the NLRP1 inflammasome in its precursor form following the recruitment of caspase caspa. Its subsequent activation causes the cleavage of the midformed pro-il1b and results in il1b maturation and secretion in the extracellular milieu. [...] | Deafness, autosomal dominant 5. | 0.906 |
| caspb | pjvk | ENSDARP00000068268 | ENSDARP00000124142 | Caspase b subunit p10; Thiol protease which cleaves IL-1 beta (il1b), releasing the mature cytokine which is involved in a variety of inflammatory processes, and mediates apoptosis. Component of the NLRP1 inflammasome, which plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, recruited to the NLRP1 inflammasome in its precursor form following the recruitment of caspase caspa. Its subsequent activation causes the cleavage of the midformed pro-il1b and results in il1b maturation and secretion in the extracellular milieu. [...] | Pejvakin. | 0.815 |
| cela1.4 | caspb | ENSDARP00000035387 | ENSDARP00000068268 | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | Caspase b subunit p10; Thiol protease which cleaves IL-1 beta (il1b), releasing the mature cytokine which is involved in a variety of inflammatory processes, and mediates apoptosis. Component of the NLRP1 inflammasome, which plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, recruited to the NLRP1 inflammasome in its precursor form following the recruitment of caspase caspa. Its subsequent activation causes the cleavage of the midformed pro-il1b and results in il1b maturation and secretion in the extracellular milieu. [...] | 0.604 |
| cela1.4 | cpa1 | ENSDARP00000035387 | ENSDARP00000024981 | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | Carboxypeptidase A1 (pancreatic). | 0.420 |
| cela1.4 | cpa4 | ENSDARP00000035387 | ENSDARP00000064203 | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | Carboxypeptidase A4. | 0.420 |
| cela1.4 | gsdmea | ENSDARP00000035387 | ENSDARP00000125872 | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | Gasdermin Ea. | 0.719 |
| cela1.4 | gsdmeb | ENSDARP00000035387 | ENSDARP00000059251 | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | Deafness, autosomal dominant 5. | 0.595 |
| cela1.4 | ltb4r2a | ENSDARP00000035387 | ENSDARP00000142395 | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | Leukotriene B4 receptor 2a. | 0.501 |
| cela1.4 | ltb4r2b | ENSDARP00000035387 | ENSDARP00000070796 | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | Leukotriene B4 receptor 2b. | 0.458 |
| cela1.4 | pjvk | ENSDARP00000035387 | ENSDARP00000124142 | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | Pejvakin. | 0.685 |
| cpa1 | cela1.4 | ENSDARP00000024981 | ENSDARP00000035387 | Carboxypeptidase A1 (pancreatic). | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | 0.420 |
| cpa4 | cela1.4 | ENSDARP00000064203 | ENSDARP00000035387 | Carboxypeptidase A4. | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | 0.420 |
| gsdmea | caspb | ENSDARP00000125872 | ENSDARP00000068268 | Gasdermin Ea. | Caspase b subunit p10; Thiol protease which cleaves IL-1 beta (il1b), releasing the mature cytokine which is involved in a variety of inflammatory processes, and mediates apoptosis. Component of the NLRP1 inflammasome, which plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, recruited to the NLRP1 inflammasome in its precursor form following the recruitment of caspase caspa. Its subsequent activation causes the cleavage of the midformed pro-il1b and results in il1b maturation and secretion in the extracellular milieu. [...] | 0.960 |
| gsdmea | cela1.4 | ENSDARP00000125872 | ENSDARP00000035387 | Gasdermin Ea. | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | 0.719 |
| gsdmeb | caspb | ENSDARP00000059251 | ENSDARP00000068268 | Deafness, autosomal dominant 5. | Caspase b subunit p10; Thiol protease which cleaves IL-1 beta (il1b), releasing the mature cytokine which is involved in a variety of inflammatory processes, and mediates apoptosis. Component of the NLRP1 inflammasome, which plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, recruited to the NLRP1 inflammasome in its precursor form following the recruitment of caspase caspa. Its subsequent activation causes the cleavage of the midformed pro-il1b and results in il1b maturation and secretion in the extracellular milieu. [...] | 0.906 |
| gsdmeb | cela1.4 | ENSDARP00000059251 | ENSDARP00000035387 | Deafness, autosomal dominant 5. | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | 0.595 |
| ltb4r2a | cela1.4 | ENSDARP00000142395 | ENSDARP00000035387 | Leukotriene B4 receptor 2a. | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | 0.501 |
| ltb4r2b | cela1.4 | ENSDARP00000070796 | ENSDARP00000035387 | Leukotriene B4 receptor 2b. | Chymotrypsin-like elastase family member 1, tandem duplicate 4; Belongs to the peptidase S1 family. | 0.458 |