STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kcnk5aPotassium channel, subfamily K, member 5a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (513 aa)    
Predicted Functional Partners:
kcnj16
Potassium inwardly rectifying channel subfamily J member 16.
      
 0.557
asic1b
Acid-sensing ion channel 1B; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.513
phox2ba
Paired-like homeobox 2Ba.
   
  
 0.495
asic4a
Acid-sensing ion channel 4-A; Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride.
      
 0.486
asic4b
Acid-sensing ion channel 4-B; Probable cation channel with high affinity for sodium. Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC4 subfamily.
      
 0.485
kcnj13
Potassium inwardly rectifying channel subfamily J member 13.
   
  
 0.469
panx3
Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
      
 0.452
slc12a7b
Solute carrier family 12 member 7b.
      
 0.452
edrf1
Erythroid differentiation regulatory factor 1.
   
  
 0.447
trpc3
Transient receptor potential cation channel, subfamily C, member 3; Belongs to the transient receptor (TC 1.A.4) family.
   
  
 0.443
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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